What condition is identified as an internal cause of chronic renal failure (CRF)?

Chronic renal failure (CRF), also known as chronic kidney disease (CKD), can arise from a variety of underlying health issues. Among the options listed, glomerulonephritis is particularly recognized as an internal cause of CRF.

Glomerulonephritis refers to inflammation of the kidney's filtering units (glomeruli). This condition can result from several internal factors, including autoimmune diseases, infections, or conditions that affect the body's immune response. The inflammation leads to damage in the glomeruli, impairing the kidneys' ability to filter waste and fluids from the blood effectively. Over time, this damage can progress to chronic renal failure as kidney function declines.

On the other hand, while diabetes and hypertension are significant contributors to chronic kidney disease, they primarily act as external risk factors or underlying systemic conditions that can lead to kidney damage, rather than being classified as internal causes like glomerulonephritis. Kidney stones are typically related to external factors and cause acute rather than chronic problems unless they lead to recurrent damage, which is not the primary focus in terms of internal causes.